On the “Software control of matter” blog

There’s some interesting activity on the blog associated with the EPSRC Ideas Factory “Software control of matter”. In response to my call for contributions, we’ve had detailed and interesting comments from Jim Moore, “Nanoenthusiast”, Robert Freitas, Chris Phoenix and Phillip Huggan. There’s a post from Jack Stilgoe, one of the mentors for the Ideas Factory, explaining what interests him about this experiment. I hope we’ll soon have other posts from other participants and mentors.

Please visit the blog and add your own thoughts – all ideas and contributions are welcome.

Software control of matter – your ideas welcome

The ‘Ideas Factory’ on Software control of matter – in which a group of scientists from different backgrounds spend a week brainstorming new and innovative approaches to a difficult problem – is just over a week away. I’m directing the activity, the outcome of which, we hope, will be novel research proposals, for which £1.5 million has been set aside to fund by the UK’s Engineering and Physical Sciences Research Council.

We were very gratified by the response, and from the applications we received we’ve selected a great group of scientists, from many different disciplines, including supramolecular chemistry, scanning probe microscopy, surface science and computer science, and ranging from some of the UK’s most eminent nanoscientists to young research fellows and postdocs. We’d like to open the process up to anyone interested, so we’ve set up a public blog for the Ideas Factory.

When the sandpit begins, on January 8, we’ll be writing about the process as it happens. But we’d also be very interested in any ideas any readers of the blog might have. You might have an opinion about how we might achieve this goal in practise; you might have thoughts about what kinds of materials one might hope to make in this way; or you might have thoughts about why – for what social benefit, or economic gain – you might want to make these materials and devices. All readers are invited to comment on the thoughts they might have through the comment facility on the Ideas Factory blog. Towards the end of next week, I’ll start putting up some posts asking for comments, and if we get any suggestions, we will feed the suggestions in to the participants of the Ideas Factory, using the blog to report back reactions. One of the mentors for the Ideas Factory – Jack Stilgoe, from the thinktank Demos – will collate and report the comments to the group. Jack’s a long-time observer of the nanotech scence, but he’s not a nanoscientist himself, so he won’t have any preconceptions of what might or might not work.

Playing God

I went to the Avignon nanoethics conference with every intention of giving a blow-by-blow account of the meeting as it happened, but in the end it was so rich and interesting that it took all my attention to listen and contribute. Having got back, it’s the usual rush to finish everything before the holidays. So here’s just one, rather striking, vignette from the meeting.

The issue that always bubbles below the surface when one talks about self-assembly and self-organisation is whether we will be able to make something that could be described as artificial life. In the self-assembly session, this was made very explicit by Mark Bedau, the co-founder of the European Center for Living Technology and participant in the EU funded project PACE (Programmable Artificial Cell Evolution), whose aim is to make an entirely synthetic system that shares some of the fundamental characteristics of living organisms (e.g. metabolism, reproduction and evolution). The Harvard chemist George Whitesides, (who was sounding more and more the world-weary patrician New Englander) described the chances of this programme being successful as being precisely zero.

I sided with Bedau on this, but what was more surprising to me was the reaction of the philosophers and ethicists to this pessimistic conclusion. Jean-Pierre Dupuy, a philosopher who has expressed profound alarm at the implications of loss of control implied by the idea of exploiting self-organising systems in technology, said that, despite all his worries, he would be deeply disappointed if this conclusion was true. A number of people commented on the obvious fear that people would express that making synthetic life would be tantamount to “playing God”. One speaker talked about the Jewish traditions connected with the Golem to insist that in that tradition the aspiration to make life was by itself not necessarily wrong. And, perhaps even more surprisingly, the bioethicist William Hurlbut, a member of the (US) President’s Council on Bioethics and a prominent Christian bioconservative, also didn’t take a very strong position on the ethics of attempting to make something with the qualities of life. Of course, as we were reminded by the philosopher and historian of science Bernadette Bensaude-Vincent, there have been plenty of times in the past when scientists have proclaimed that they were on the verge of creating life, only for this claim to turn out to be very premature.

Against nanoethics

I spent a day the week before last in the decaying splendour of a small castle outside Edinburgh, in the first meeting of a working group considering the ethics of human enhancement. This is part of a European project on the ethics of nanotechnology and related technologies – Nanobioraise. It was a particular pleasure to meet Alfred Nordmann, of the Technical University of Darmstadt – a philosopher and historian of science who has written some thought provoking things about nanotechnology and the debates surrounding it.

Nordmann’s somewhat surprising opening gambit was to say that he wasn’t really in favour of studying the ethics of human enhancement at all. To be more precise, he was very suspicious of efforts to spend a lot of time thinking about the ethics of putative long-term developments in science and technology, such as the transcendence of human limitations by human enhancement technologies, or an age of global abundance brought about by molecular nanotechnology. Among the reasons for his suspicion is a simple consideration of the opportunity cost of worrying about something that may never happen – “ethical concern is a scarce resource and must not be squandered on incredible futures, especially where on-going developments demand our attention.” But Nordmann also identifies some more fundamental problems with this way of thinking.

He identifies the central rhetorical trick of speculative ethics as being an elision between “if” and “then”: we start out identifying some futuristic possibility along the lines of “if MNT is possible “, then we identify some ethical consequence from it “then we need to prepare for an age of global abundance, and adjust our economies accordingly”, which we take as a mandate for action now, foreshortening the conditional. In this way, the demand for early ethical consideration lends credence to possible futures whose likelihood hasn’t yet been tested rigorously. This gives a false impression of inevitability, which shuts off the possibility that we can steer or choose the path that technology takes, and it distracts us from more pressing issues. It’s also notable that some of those who are most prone to this form of argument are those with a strong intellectual or emotional stake in the outcome in question.

His argument is partly developed in unpublished article “Ignorance at the Heart of Science? Incredible Narratives on Brain-Machine Interfaces”, which is well worth reading. It closes with a set of recommendations, referring back to an earlier EU report coordinated by Nordman, Converging Technologies – Shaping the Future of European Societies, which recommends that:

  • “science policy attends also to the limits of technical feasibility, suggesting for example that one should scientifically scrutinize the all too naive assumptions, if not (citing Dan Sarewitz) “conceptual cluenessness” about thought and cognition that underwrites the US-report on NBIC convergence.
  • Along the same lines, a committee of historians and statisticians should produce a critical assessment of Ray Kurzweil’s thesis about exponential growth.
  • Also, as Jürgen Altmann has urged, we need an Academy report about the Drexlerian vision of nanotechnology – is molecular manufacturing a real possibility or not?
  • Finally and most generally, we need scientists and engineers who have the courage to publically distinguish between what is physically possible and what is technically feasible.
  • As a citizen, I am overtaxed if I am to believe and even to prepare for the fact that humans will soon engineer everything that does not contradict outright a few laws of nature.”

    In short, Nordmann believes that nanoethics needs to be done more ethically.

    It’s all about metamaterials

    A couple of journalists have recently asked me some questions about the EPSRC Ideas Factory on software control of matter that I am directing in January. The obvious question is whether software control of matter – which was defined as “a device or scheme that can arrange atoms or molecules according to an arbitrary, user-defined blueprint” – will be possible. I don’t know the answer to this – in some very limited sense (for example, the self-assembly of nanostructures based on DNA molecules with specified sequences) it is possible now, but whether these very tentative steps can be fully generalised is not yet clear (and if it was clear, then there would be no point in having the Ideas Factory). More interesting, perhaps is the question of what one would do with such a technology if one had it. Would it lead to, for example, the full MNT vision of Drexler, with personal nanofactories based on the principles of mechanical engineering executed with truly atomic precision?

    I don’t think so. I’ve written before of the difficulties that this project would face, and I don’t want to repeat that argument here. Instead, I want to argue that this mechanically focused vision of nanotechnology actually misses the biggest opportunity that this level of control over matter would offer – the possibility of precisely controlling the interactions between electrons and light within matter. The key idea here is that of the “metamaterial”, but the potential goes much further than simply designing materials: instead, the prize is the complete erosion of the distinction we have now between a “material” and a “device”.

    A “metamaterial” is the name given to a nanoscale arrangement of atoms that gives rise to new electronic,magnetic or optical properties that would not be obtainable in a single, homogenous material. It’s been known for some time, for example, that structures of alternating layers of different semiconductors can behave, as far as an electron is concerned, as a new material with entirely new semiconducting properties. The confinement of electrons in “quantum dots” – nanoscale particles of semiconductors – profoundly changes the quantum states allowed to an electron, and clever combinations of quantum dots and layered structures yield novel lasers now, and the promise of quantum information processing devices in the future. For light, the natural gemstone opal – formed by the self-assembly of spherical particles in ordered arrays – offers a prototype for metamaterials that interact with light in interesting and useful ways. This field has been recently energised by the theoretical work of John Pendry, , at Imperial College, who has demonstrated that in principle arrays of patterned dielectrics and conductors can behave as materials with a negative refractive index.

    This notion of optical metamaterials has achieved media notoriety as a route to making “invisibility cloaks” (see this review in Science for a more sober assessment). But the importance of these materials is much more general than that – in principle, if one can arrange the components of the metamaterial with nanoscale precision to some pattern that one calculates, one can guide light to go pretty much anywhere. If you combine this with the ability from semiconductor nanotechnology to manipulate electronic states, and from magnetic nanotechnology to manipulate electron spin, one has the potential for an integrated information technology of huge power. This will probably use not just the charge of the electron, as is done now, but its spin (spintronics) and/or its quantum state (quantum computing). There are, of course, some big ifs here, and I’m far from being confident that the required degree of generality, precision and control is possible. But I am sure that if something like a “matter compiler” is possible, it is manipulating photons and electrons, rather than carrying out fundamentally mechanical operations, that its products will be used for.

    On nanotechnology and biology

    The second issue of Nature Nanotechnology is now available on-line (see here for my comments on the first issue). I think this issue is also free to view, but from next month a subscription will be required.

    Among the articles is an overview of nanoelectronics, based on a report from a recent conference, and a nice letter from a Belgian group describing the placement and reaction of individual macromolecules at surfaces using an AFM . The regular opinion column this month is contributed by me, and concerns one of my favourite themes: Is it possible to use modern science and engineering techniques to improve on nature, or has evolution already found the best solutions?

    Software control of matter at the atomic and molecular scale

    The UK’s physical sciences research council, the EPSRC, has just issued a call for an “ideas factory” with the theme “Software control of matter at the atomic and molecular scale”, a topic proposed by Nottingham University nanophysicist Philip Moriarty. The way these programs work is that 20-30 participants, selected from many different disciplines, spend a week trying to think through new and innovative approaches to a very challenging problem. At the end of the process, it is hoped that some definite research proposals will emerge, and £1.5 million (i.e. not far short of US$ 3 million) has been set aside to fund these. The challenge, as defined by the call, is as follows:

    “Can we design and construct a device or scheme that can arrange atoms or molecules according to an arbitrary, user-defined blueprint? This is at the heart of the idea of the software control of matter – the creation, perhaps, of a “matter compiler” which will interpret software instructions to output a macroscopic product in which every atom is precisely placed. Even partial progress towards this goal would significantly open up the range of available functional materials, permitting meta-materials with interesting electronic, optoelectronic, optical and magnetic properties.

    One route to this goal might be to take inspiration from 3-d rapid prototyping devices, and conceive of some kind of pick-and-place mechanism operating at the atomic or molecular level, perhaps based on scanning probe techniques. On the other hand, the field of DNA nanotechnology gives us examples of complex structures built by self- assembly, in which the program to guide the construction is implicit within the structure of the building blocks themselves. This problem, then, goes beyond surface chemistry and the physics of self-assembly to some fundamental questions in computer science.

    This ideas factory should attract surface physicists and chemists, including specialists in scanning probe and nanorobotic techniques, and those with an interest in self-assembling systems. Theoretical chemists, developmental biologists, and computer scientists, for example those interested in agent-based and evolutionary computing methods and emergent behaviour, will also be able to contribute. “

    I’d encourage anyone who is eligible to receive EPSRC research funding (i.e. scientists working in UK universities and research institutes, broadly speaking) who is interested in taking part in this event to apply using the form on the EPSRC website. One person who won’t be getting any funding from this is me, because I’ve accepted the post of director of the activity.

    Was Feynman the founder of nanotechnology?

    Amidst all the controversy about what nanotechnology is and isn’t, one thing that everyone seems to agree on is the visionary role of Richard Feynman as the founding father of the field, through his famous lecture, There’s plenty of room at the bottom. In a series of posts I made here a year or so ago (Re-reading Feynman Part 1, Part 2, Part 3), I looked again, with the benefit of hindsight, at what Feynman actually said in this lecture, in the light of the way nanoscience and technology has developed. But does the claim that this lecture launched nanotechnology stand up to critical scrutiny?

    This question was considered in a fascinating article by Chris Toumey called Apostolic Succession (PDF file). The article, published last year in Caltech’s house science magazine (just as Feynman’s original lecture was), takes a cool look at the evidence that might underpin the claim that “Plenty of Room at the Bottom” really was the foundational text for nanotechnology. The first place to look is in citations – occasions when the article was cited by other writers. Perhaps surprisingly, Plenty of Room was cited just 7 times in the two decades of the 60’s and 70’s, and the annual citation rate didn’t get into double figures until 1992. Next, Toumey directly questioned leading figures from nanoscience on the degree to which they were influenced by the Feynman lecture. The answers – from scientists of the standing of Binnig, Rohrer, and Eigler, Mirkin and Whitesides – were overwhelmingly negative. The major influence of the Feynman lecture, Toumey concludes, has been through the mediation of Drexler, who has been a vocal champion of the paper since coming across it around 1980.

    Toumey draws three conclusions from all this. As he puts it, “The theory of apostolic succession posited that first there was “Plenty of Room”; then there was much interest in it; and finally that caused the birth of nanotechnology. My analysis suggests something different: first there was “Plenty of Room”; then there was very little interest in it; meanwhile, there was the birth of nanotechnology, independent of it; and finally there was a retroactive interest in it. I believe we can credit much of the rediscovery to Drexler, who has passionately championed Feynman’s paper.” As for why such a retroactive interest appeared, Toumey makes the obvious point that attaching one’s vision to someone with the genius, vision and charisma of Feynman is an obvious temptation. Finally, though, Toumey asks “how selective is the process of enhancing one’s work by retroactively claiming the Feynman cachet? “ The point here, and it is an important one, is that, as I discussed in my re-readings of Feynman, this lecture talked about many things and it requires a very selective reading to claim that Feynman’s musings supported any single vision of nanotechnology.

    Toumey (who is from the centre for nanoScience & Technology Studies at the University of South Carolina) is an anthropologist by training, so it’s perhaps appropriate that his final conclusion is expressed in rather anthropological terms: “We can speculate about why “Plenty of Room” was rediscovered. Perhaps it shows us that a new science needed an authoritative founding myth, and needed it quickly. If so, then pulling Feynman’s talk off the shelf was a smart move because it gave nanotech an early date of birth, it made nanotech coherent, and it connected nanotech to the Feynman cachet.”

    My thanks to Peter Rodgers for bringing this article to my attention.

    A brief update

    My frequency of posting has gone down in the last couple of weeks due to a combination of excessive busy-ness and a not wholly successful attempt to catch up with stuff before going on holiday. Here’s a brief overview of some of the things I would have written about if I’d had more time.

    The Nanotechnology Engagement Group (which I chair) met last week to sketch out some of the directions of its second policy report, informed in part by an excellent workshop – Terms of Engagement – held in London a few weeks ago. The workshop brought together policy-makers, practitioners of public engagement, members of the public who had been involved in public engagement events about nanotechnology, and scientists, to explore the different expectations and aspirations these different actors have, and the tensions that arise when these expectations aren’t compatible.

    The UK government’s funding body for the physical sciences, EPSRC, held a town meeting to discuss its new draft nanotechnology strategy last week. About 50 of the UKs leading nanoscientists attended; To summarise the mood of the meeting, people were pleased that EPSRC was drawing up a strategy, but they thought that the tentative plan was not nearly ambitious enough. EPSRC and its Strategic Working Group on Nanotechnology (of which I am a member) will be revising the draft strategy in line with these comments and the result should be presented to EPSRC Council for approval in October.

    The last two issues of Nature have much to interest the nanotechnologist. Nanotubes unwrapped introduces the idea of using exfoliated graphite as a reinforcing material in composites; this should produce many of the advantages that people hope for in nanotube composites (but which have not yet so far fully materialised) at much lower cost. Spintronics at the atomic level describes a very elegant experiment in which a single manganese atom is introduced as a substitutional dopant on a gallium arsenide surface using a scanning tunnelling microscope, to probe its magnetic interactions with the surroundings. This week’s issue also includes a very interesting set of review articles about microfluidics, including pieces by George Whitesides and Harold Craighead, to which there is free access.

    Rob Freitas has put together a website for his Nanofactory collaboration. Having complained on this blog before that my own critique of MNT proposals has been ignored by MNT proponents, it’s only fair for me to recognise that this site has a section about technical challenges which explicitly acknowledges such critiques with these positive words:
    “This list, which is almost certainly incomplete, parallels and incorporates the written concerns expressed in thoughtful commentaries by Philip Moriarty in 2005 and Richard Jones in 2006. We welcome these critiques and would encourage additional constructive commentary – and suggestions for additional technical challenges that we may have overlooked – along similar lines by others.”

    Finally, in a not totally unrelated development, the UKs funding council, EPSRC, will be running an Ideas Factory on the subject of Matter compilation via molecular manufacturing: reconstructing the wheel. The way this program works is that participants spend a week generating new ideas and collaborations, and at the end of it £1.45 million funding is guaranteed for the best proposals. I’ve been asked to act as the director of this activity, which should take place early in the New Year.